As it happens, there are PIXs between the hobbit server & all the Exchange servers. However, they've all been there for ages (years in some cases).
I'll have a chat with our resident Cisco guru & see if he made any changes at our end around 6th June, when things stopped working.
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From: Rob MacGregor [mailto:rob.macgregor at gmail.com]
You wouldn't happen to have a Cisco PIX/ASA between the hobbit host and the mail server, with it configured to do "fixup"? Those are known for breaking things ;)
Rob MacGregor